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KMID : 1100220100090020069
Dementia and Neurocognitive Disorders
2010 Volume.9 No. 2 p.69 ~ p.73
Recurrent Stroke-Like Episodes in a Patient with Elderly Onset Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-Like Episodes (MELAS)


Abstract
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) uncommonly develops after the age of 40. We describe a patient with MELAS whose first strokelike episode presented at age 65, followed by two more episodes. The brain MR imaging for each stroke-like episode demonstrated hyperintense lesion in diffusion weighted image (DWI),and variable signal intensities in apparent diffusion coefficient (ADC) maps in temporo-parietal and occipital regions. We diagnosed the patient as MELAS with 3243A>G point mutation.
KEYWORD
MELAS, Elderly, Stroke, MR imaging
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